Metformin extended-release versus metformin immediate-release for adults with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials.
Published 2021 · Aedrian A Abrilla, A Nico Nahar I Pajes, Cecilia A Jimeno
Diabetes research and clinical practice
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Abstract
Abstract removed due to Elsevier request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Key takeawayMetformin extended-release (MXR) is associated with statistically worse but likely clinically insignificant HbA1c lowering, similar plasma glucose control, and minimal improvement of metformin intolerance compared to metformin immediate-release (MIR).
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.