Aniline is selectively brominated by use of molecular bromine adsorbed on zeolite 5A in carbon tetrachloride to give monobromoanilines. Coexistence of organic bases such as pyridine and 2,6-lutidine increases the yield and selectivity of 4-bromoaniline. o-, m-, and p-Toluidines are also monobrominated selectively according to the present procedure.

Selective monobromination of aniline derivatives using bromine adsorbed on zeolite 5A in carbon tetrachloride can produce 4-bromoaniline, o-, m-, and p-toluidines, with increased yield and selectivity when coexisting with organic

Paper

Selective monobromination of aniline derivatives by use of bromine adsorbed on zeolite 5A.

References

Citations