New multifunctional copoly(2-oxazoline) nanoparticles were prepared for cell studies. The polymer contains double-bond side chains as potential reaction sites for "thio"-click reactions as well as a fluorescein label covalently bound to the polymer backbone. Using the nanoprecipitation technique, spherical nanoparticles of 200-800 nm were obtained. Confocal laser scanning microscopy measurements revealed the cellular uptake of the nanoparticles.

Multifunctional copoly(2-oxazoline) nanoparticles show potential for biological applications, with potential for "thio"-click reactions and fluorescence labeling.

Multifunctional Poly(2-oxazoline) Nanoparticles for Biological Applications.

Key Takeaway: Multifunctional copoly(2-oxazoline) nanoparticles show potential for biological applications, with potential for "thio"-click reactions and fluorescence labeling.