Neurotoxic effects in adult mice neonatally exposed to 3,3'4,4'5-pentachlorobiphenyl or 2,3,3'4,4'-pentachlorobiphenyl. Changes in brain nicotinic receptors and behaviour.

doi:10.1016/S1382-6689(97)10002-3

Paper

Neurotoxic effects in adult mice neonatally exposed to 3,3'4,4'5-pentachlorobiphenyl or 2,3,3'4,4'-pentachlorobiphenyl. Changes in brain nicotinic receptors and behaviour.

Published 1998 · P. Eriksson, A. Fredriksson

Environmental toxicology and pharmacology

Q1 SJR score

63

Citations

6

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Abstract

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Non-RCT

Animal Study

Study Snapshot

Neonatal exposure to 3,3′,4,4′,5-pentachlorobiphenyl can cause persistent behavioral changes and affect learning and memory functions in adult mice, while 2,3,3′,4,4′-pentachlorobiphenyl does not show significant behavioral changes.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Neurotoxic effects in adult mice neonatally exposed to 3,3'4,4'5-pentachlorobiphenyl or 2,3,3'4,4'-pentachlorobiphenyl. Changes in brain nicotinic receptors and behaviour.

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