Paper

Nortriptyline induces mitochondria and death receptor-mediated apoptosis in bladder cancer cells and inhibits bladder tumor growth in vivo.

Published Aug 15, 2015 · K. Chiu, C. Su, Sheau-Yun Yuan

European journal of pharmacology

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Abstract

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In Vitro Study

Rigorous Journal

Study Snapshot

Nortriptyline induces both intrinsic and extrinsic apoptosis in bladder cancer cells, potentially making it a useful chemotherapeutic agent for bladder cancer in humans.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Nortriptyline induces mitochondria and death receptor-mediated apoptosis in bladder cancer cells and inhibits bladder tumor growth in vivo.

References

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