A novel quinazoline-based analog induces G2/M cell cycle arrest and apoptosis in human A549 lung cancer cells via a ROS-dependent mechanism.

doi:10.1016/j.bbrc.2017.03.034

Paper

A novel quinazoline-based analog induces G2/M cell cycle arrest and apoptosis in human A549 lung cancer cells via a ROS-dependent mechanism.

Published Apr 29, 2017 · Haining Shi, Yan Li, Xiaorong Ren

Biochemical and biophysical research communications

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16

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Abstract

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In Vitro Study

Study Snapshot

QNZ-A, a novel quinazoline-based analog, effectively induces G2/M cell cycle arrest and apoptosis in human A549 lung cancer cells through a ROS-dependent mechanism.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

A novel quinazoline-based analog induces G2/M cell cycle arrest and apoptosis in human A549 lung cancer cells via a ROS-dependent mechanism.

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