Opioids in clinical practice
Published Jan 3, 2020 · I. Zaporowska-Stachowiak, M. Oduah, Magdalena Celichowska
Palliative Medicine in Practice
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Abstract
The treatment of pain improves quality of life. Opioids are commonly prescribed painkillers. The side effects of opioids depend on the route of administration, dosage, drug metabolism, comorbid diseases and the patient’s general condition. Despite many beneficial effects, opioids can lead to increased mortality in heart failure, myocardial infarction, pulmonary oedema, and COPD. This article reviews specific uses of opioid medications. Opioids induce immunosuppression, and may undergo drug-drug interactions, especially during polytherapy or polypragmasia.
Study Snapshot
Key takeawayOpioids can improve pain quality and reduce side effects, but may increase mortality in certain conditions and may cause drug-drug interactions.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.