Paper
Pharmacology and mechanism of action of pregabalin: The calcium channel α2–δ (alpha2–delta) subunit as a target for antiepileptic drug discovery
Published Feb 1, 2007 · C. Taylor, T. Angelotti, E. Fauman
Epilepsy Research
453
Citations
8
Influential Citations
Abstract
Abstract removed due to Elsevier request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Key takeawayPregabalin reduces neuronal excitability and seizures by binding to the alpha2–delta subunit of voltage-gated calcium channels, potentially through reduced neurotransmitter release.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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