Natural products and drug discovery
Published Sep 29, 2022 · D. Newman
National Science Review
38
Citations
1
Influential Citations
Abstract
Abstract This review covers the recent history of a series of very important natural products and their derivatives that are currently in use or under evaluation in the areas of anti-infectives, important cancer treatments that include antibody drug conjugates, followed by a discussion of type 2 diabetes (T2DM) drugs and angiotensin converting enzyme inhibitors. The current structures of the agents are shown, though in the case of some peptides used in T2DM drugs the standard single letter abbreviation for an amino acid is used.
Study Snapshot
Key takeawayNatural products and their derivatives are crucial for anti-infectives, cancer treatments, type 2 diabetes drugs, and angiotensin converting enzyme inhibitors.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.