Based on recent research, an upper limit of safe intake (ULSI) for leucine is proposed for healthy adults: 0.53 g/(kg·d). Because leucine has been used as a dietary supplement for many years in people practicing exercise and sport, further study with long-term exposure to leucine in this specific subpopulation should be performed to eventually adjust the ULSI.

The upper limit of safe intake for leucine in healthy adults is 0.53 g/(kgd), with further study needed to adjust it for exercise and sport practitioners.

Paper

A proposal for an upper limit of leucine safe intake in healthy adults.

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