PSYCHOSES ASSOCIATED WITH PERNICIOUS ANEMIA

doi:10.1001/ARCHNEURPSYC.1937.02260200120010

Paper

PSYCHOSES ASSOCIATED WITH PERNICIOUS ANEMIA

Published Aug 1, 1937 · M. Herman, H. Most, N. Jolliffe

Journal of Nervous and Mental Disease

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Abstract

The occurrence of mental changes in patients having pernicious anemia was noted by Addison 1 in his classic description of the disease in 1855. Psychiatric studies of patients with this disease have since appeared only at infrequent intervals, though there are many contributions from an etiologic, neurologic and hematologic standpoint. 2 This poverty of psychiatric reports exists in spite of the high incidence of mental changes in this disease, as evidenced by the recent work of Goldhamer and his associates, 3 who reported that 64 per cent of their patients showed cerebral symptoms. Other observers, however, reported the incidence of mental changes to be from 25 to 40 per cent; for instance, Ahrens 4 reported 25 per cent, Woltman 5 39 per cent, Hulett 6 35 per cent and Weisenburg 7 40 per cent. Mental symptoms in patients with pernicious anemia that are sufficiently severe to be classified as a

Study Snapshot

Key takeawayPernicious anemia is associated with a high incidence of mental changes, with studies reporting rates between 25% and 64%.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

PSYCHOSES ASSOCIATED WITH PERNICIOUS ANEMIA

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