Radioiodinated 1-carboxamidino-4-phenylpiperazine: a potential adrenal and myocardial imaging radiopharmaceutical.

doi:10.1016/0020-708X(82)90060-6

Paper

DOI: 10.1016/0020-708X(82)90060-6

Radioiodinated 1-carboxamidino-4-phenylpiperazine: a potential adrenal and myocardial imaging radiopharmaceutical.

Published Aug 1, 1982 · R. Hanson

The International journal of applied radiation and isotopes

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

Radioiodinated 1-carboxamidino-4-phenylpiperazine shows potential as an imaging agent for myocardial and adrenomedullary diseases due to its high uptake and tissue-to-blood ratios.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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References

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Citations

DOI: 10.1038/bjc.1996.457

Evaluation of phenylpiperazines as targeting agents for neuroblastoma.

Phenylpiperazines show significant affinity for neuroblastoma, with uptake and retention characteristics similar to MIBG, making them potential targets for detection and therapy.

1996·2citations·JW Babich et al.·British Journal of Cancer

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Synthesis and evaluation of 1-[11C]methyl-4-aryl-piperazinium salts as myocardial imaging agents.

1-[11C]methyl-1-alkyl-4-phenylpiperazinium cations show potential as myocardial imaging agents, with high concentrations in the rat heart and canine heart at 5 minutes.

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Synthesis of 4-(4-iodophenyl)piperazine and the 1-carboxamidino derivative

The synthesis of 4-(4-iodophenyl)piperazine and its carboxamidino derivative shows potential as a potential myocardial imaging radiopharmaceutical.

1985·7citations·R. Hanson et al.·Journal of Heterocyclic Chemistry

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astargeting agents forneuroblastoma

Phenylpiperazines show significant affinity for neuroblastoma with uptake and retention characteristics similar to MIBG.

1996·0citations·J. Babich

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Synthesis and biodistribution of [125I]iodo- and [75Se]seleno-ergoline derivatives.

Both [125I]iodo- and [75Se]seleno-ergoline derivatives show good uptake by the adrenals and brain, with 75 Se-2 showing higher adrenal uptake and brain-to-blood ratios.

1987·6citations·S. Sadek et al.·International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes

International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes