L. Arias, A. Arteta, R. Giraldo
Dec 1, 2007
American Journal of Transplantation
The Banff Classification of Renal Allograft Pathology is used internationally for scoring and classifying rejection in kidney transplant biopsies. This score system has gone through a number of modifications since it was first published in 1993. Criteria for diagnosis are changing as new knowledge is accumulated, studies demonstrate the importance of features not previously considered, and ancillary studies are developed for more precise determination of graft dysfunction causes. The 2005-updated Banff schema, published in 2007 (1), recognizes antibodymediated rejection (AMR), in addition to the traditional category of acute and chronic active T-cell-mediated rejection. The more sophisticated approach to renal biopsy study permits refinement in diagnosis and specific therapeutic approaches.