Resolution of 1-(4-amino-3-chloro-5-cyanophenyl)-2-bromo-1-ethanol by lipase mediated enantioselective alcoholysis, hydrolysis and acylation

doi:10.1016/S0957-4166(98)00252-3

Paper

Resolution of 1-(4-amino-3-chloro-5-cyanophenyl)-2-bromo-1-ethanol by lipase mediated enantioselective alcoholysis, hydrolysis and acylation

Published Jul 3, 1998 · S. Conde, M. Fierros, M. I. Rodríguez-Franco

Tetrahedron-asymmetry

UNKNOWN SJR score

10

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Abstract

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Study Snapshot

Lipase-catalyzed alcoholysis, hydrolysis, and acylation effectively resolve 1-(4-amino-3-chloro-5-cyanophenyl)-2-bromo-1-ethanol, providing an intermediate for the synthesis of a new adrenergic

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Resolution of 1-(4-amino-3-chloro-5-cyanophenyl)-2-bromo-1-ethanol by lipase mediated enantioselective alcoholysis, hydrolysis and acylation

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