A positive role for histone acetylation in transcription factor access to nucleosomal DNA

doi:10.1016/0092-8674(93)90051-Q

Paper

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

Published Jan 15, 1993 · Daniel Y. Lee, J. Hayes, D. Pruss

Cell

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1,146

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34

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Abstract

Abstract removed due to Elsevier request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

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Study Snapshot

Key takeawayAcetylation of core histones facilitates transcription factor access to DNA, potentially influencing chromatin accessibility to regulatory molecules.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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A positive role for histone acetylation in transcription factor access to nucleosomal DNA

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