Small-bowel continuity: A crucial factor in determining survival in gastroschisis
E. Cusick, R. Spicer, J. Beck
2005
Citations
31
Citations
Journal
Pediatric Surgery International
Full text
Semantic Scholar
Key Takeaway Key Takeaway: Small-bowel continuity is crucial in determining survival in gastroschisis patients, with small-bowel atresia/stenosis being a significant prognostic factor.
Abstract
A retrospective analysis of a series of 63 cases of gastroschisis managed over an 11-year period distinguished a single statistically significant prognostic factor. There were 6 (9.5%) deaths, of which 4 occurred in the 8 infants with small-bowel atresia/stenosis (P < 0.005, Fisher's exact test). One died at 48 h and the remaining 3 of liver disease related to total parenteral nutrition. Of the 4 survivors, 1 developed a late biliary stricture necessitating hepaticoenterostomy but is alive and well aged 4 years. The remaining 3, following initially prolonged hospitalisations and multiple operations, are alive and well after 2, 4 and 7 years. In 3 patients the atresi1 was not detected at the primary operation. The small number of cases of gastroschisisassociated small-bowel atresia seen in any one unit may conceal the importance of the problem, and limits experience in the approach to management.