Paper
The Social Salience Hypothesis of Oxytocin
Published Feb 1, 2016 · S. Shamay-Tsoory, A. Abu-Akel
Biological Psychiatry
Q1 SJR score
697
Citations
31
Influential Citations
Abstract
Abstract removed due to Elsevier request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Key takeawayOxytocin regulates the salience of social cues through its interaction with the dopaminergic system, affecting various aspects of social behavior and potentially causing antisocial effects.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
Intranasal Oxytocin: Myths and Delusions
Intranasal oxytocin has limited effects on the cerebrospinal fluid, and proper dose-response studies are needed to confirm its effectiveness.
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Oxytocin imbalances in the brain may contribute to anxiety disorders, particularly those with a social component, and chronic treatment may increase anxiety.
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Oxytocin improves mentalizing – Pronounced effects for individuals with attenuated ability to empathize
Oxytocin enhances mentalizing abilities, particularly for individuals with lower empathy scores, but its effects depend on baseline social-cognitive skills like empathy.
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Psychoneuroendocrinology
Intranasal administration of oxytocin increases compassion toward women.
Oxytocin enhances compassion toward women, but not toward men, suggesting that compassion evolved as a caregiving behavior to help vulnerable individuals.
2015·33citations·Sharon Palgi et al.·Social cognitive and affective neuroscience
Social cognitive and affective neuroscience
Effects of Oxytocin on Attention to Emotional Faces in Healthy Volunteers and Highly Socially Anxious Males
Oxytocin can reduce attentional bias for emotional faces in highly socially anxious individuals, potentially aiding in treatment for social anxiety.
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International Journal of Neuropsychopharmacology
Citations
The Moderating Role of Oxytocin in the Association Between Parental Support and Change in Secure Attachment Development
Parental support positively impacts secure attachment development, with higher oxytocin levels moderating this relationship.
2024·0citations·Samuel Budniok et al.·The Journal of Early Adolescence
The Journal of Early Adolescence
Conventional and new immunotherapies for immune system dysregulation in postpartum mood disorders: comparisons to immune system dysregulations in bipolar disorder, major depression and postpartum autoimmune thyroid disease.
Postpartum mood disorders may be linked to immune dysregulation, and anti-inflammatory and T cell boosting agents may be effective treatments for this condition.
2024·0citations·H. A. Drexhage et al.·Expert review of clinical immunology
Expert review of clinical immunology
Oxytocin neurons signal state-dependent transitions to thermogenesis and behavioral arousal in social and non-social settings
Oxytocin neurons play a role in regulating behavioral thermoregulation in mice, predicting transitions to active and quiescent huddling and predicting behavioral arousal and thermogenesis in social and non-social settings.
2024·0citations·Morgane Vandendoren et al.·bioRxiv
bioRxiv
Promoting salutogenic pathways to health through complementary and integrative health approaches
Complementary and integrative health approaches, including mind and body interventions, can help mitigate chronic stress effects and promote salutogenic pathways to health and well-being.
2024·0citations·E. Quinlan et al.·Frontiers in Psychology
Frontiers in Psychology
Polymorphic variants of the oxytocin receptor gene (OXTR rs53576) and psychosocial characteristics in adolescent
The rs53576 OXTR AA genotype is more common in boys than girls and is associated with higher emotional symptoms and communication problems with peers.
2024·0citations·K. Afonicheva et al.·Сибирский научный медицинский журнал
Сибирский научный медицинский журнал