Structure and biological properties of sodium and potassium 1-(carboxy)-1-(N-methylamide)-2-(3′,5′-di-tert-butyl)-4-hydroxyphenyl)-propionates

doi:10.1134/S1990793113010132

Paper

Structure and biological properties of sodium and potassium 1-(carboxy)-1-(N-methylamide)-2-(3′,5′-di-tert-butyl)-4-hydroxyphenyl)-propionates

Published Mar 14, 2013 · A. Volod’kin, V. Erokhin, E. Burlakova

Russian Journal of Physical Chemistry B

Q3 SJR score

4

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Sodium (1) and potassium (2) 1-(carboxy)-1-(N-methylamide)-2-(3′,5′-di-tert-butyl)-4-hydroxyphenyl)-propionates form crystal hydrates, which exist as both monomers and dimers. Quantum-chemical calculations in the PM6 approximation are used to determined the enthalpies of formation −Hfpo, thermal enthalpy Hpo, and entropy Spo of the monomers and dimers, which are indicative of the possibility of existence of the dimers of propionates of alkali metals. The biological activity of these compounds in animal and plants is demonstrated to be dependent on their concentrations. Compounds 1 and 2 turned out to be efficient in the treatment of burn injuries, cancer, and radiation damage (in vivo and in vitro), as well as in promoting the growth of cereal plants.

Study Snapshot

Sodium and potassium 1-(carboxy)-1-(N-methylamide)-2-(3′,5′-di-tert-butyl)-4-hydroxyphenyl)-propionates show potential in treating burn injuries, cancer, and radiation damage, as well as promoting cereal plant growth

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Structure and biological properties of sodium and potassium 1-(carboxy)-1-(N-methylamide)-2-(3′,5′-di-tert-butyl)-4-hydroxyphenyl)-propionates

References

Citations