Paper
Studies on the mechanism of the antimicrobial action of oleuropein.
Published Dec 1, 1972 · B. Juven, Y. Henis, B. Jacoby
The Journal of applied bacteriology
83
Citations
1
Influential Citations
Abstract
Summary: Oleuropein, the bitter principle of green olives, is surface active; this and its effect on cell membranes, as demonstrated with human erythrocytes, seems to be the basis of its antimicrobial activity. Oleuropein effected a significant leakage of glutamate, potassium and inorganic phosphate from Lactobacillus plantarum. Oleuropein had no effect on the rate of glycolysis when added to resting cells of L. plantarum but it caused a decrease in the ATP content of the cells.
In Vitro Study
Highly CitedOleuropein, the bitter principle of green olives, is antimicrobial due to its surface activity and effect on cell membranes, causing a leakage of glutamate, potassium, and inorganic phosphate from Lactobacillus plantarum.
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