Studying Peripheral Vascular Pulse Wave Velocity Using Bio-impedance Plethysmography and Regression Analysis
Ji-Jer Huang, Yang-Min Huang, A. See
Jul 2, 2017
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Key Takeaway Key Takeaway: Bioimpedance plethysmography can accurately measure peripheral vascular pulse wave velocity, with abdominal circumference and height being significant predictors, and systolic and diastolic blood pressure also influencing the PWV from the wrist to the middle finger.
Abstract
In this study, a simple bioimpedance plethysmography method was employed to measure the pulse wave velocity (PWV) from the radial artery in the wrist to the middle finger of a patient. Subsequently, electrocardiography was combined with a bioimpedance method to calculate the PWV from ECG and pulse waves to the middle finger. Experiments were conducted by employing cuffs that temporarily block blood flow to produce observable changes in the PWV. Statistical results indicated that temporary blockage of blood flow did not influence the PWV of typical healthy people. Moreover, multiple regression analysis was used to establish an equation for estimating two types of PWV and their relevance with other physiological parameters. Multiple regression analysis indicated that the abdomen circle and height are independent predictors of the PWV from the radial artery in the wrist to the middle finger (wfPWV) (r = 0.893). Systolic blood pressure (SBP) and diastolic blood pressure (DBP) are independent predictors of the PWV from the EGC T wave to the middle finger (tfPWV) (r = 0.898). Correlation analysis showed the wfPWV is significantly associated with tfPWV (r = 0.770, p < 0.01).