Synthesis of 2-substituted 7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-4-carboxylic acids

doi:10.1134/S1070428012060097

Paper

Synthesis of 2-substituted 7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-4-carboxylic acids

Published Jul 5, 2012 · D. A. Rudenko, S. Shurov, M. Kodess

Russian Journal of Organic Chemistry

Q4 SJR score

3

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Abstract2-Substituted 7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-4-carboxylic acids were synthesized by reaction of acyl- and aroylpyruvic acids with 3-amino-5,5-dimethylcyclohex-2-en-1-one. A plausible mechanism of their formation was proposed on the basis of ab initio quantum-chemical calculations.

Study Snapshot

2-Substituted 7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-4-carboxylic acids were synthesized by reacting acyl- and aroylpyruvic acids with 3-amino-5,5-dimethyl

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Paper

Synthesis of 2-substituted 7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-4-carboxylic acids

References

Citations

ANTIRADICAL ACTIVITY OF 2,5-DIARYL-8,8-DIMETHYL-3,6,7,8-TETRAHYDRO-2H-PYRIDO [4,3,2-DE]CINNOLIN-3-ONES

2,5-diaryl-8,8-dimethyl-3,6,7,8-tetrahydro-2H-pyrido[4,3,2-de]cinnolin-3-ones show no pronounced antiradical activity, suggesting another mechanism of antioxidant action.

Synthesis of 2‐Substituted 7,7‐Dimethyl‐5‐oxo‐5,6,7,8‐tetrahydroquinoline‐4‐carboxylic Acids.

2-Substituted 7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-4-carboxylic acids were synthesized by reacting acyl- and aroylpyruvic acids with 3-amino-5,5-dimethyl

Pharmacoprophylaxis of liver diseases: creating a new hepatoprotector

A new compound, pyrido [4, 3, 2] cinnol I, has been developed with hepatoprotective activity, reducing the toxic effect of carbon tetrachloride by 79.9% in rats.