Synthesis, anti-fungal and 1,3-β-D-glucan synthase inhibitory activities of caffeic and quinic acid derivatives.

doi:10.1016/j.bmc.2010.08.022

Paper

Synthesis, anti-fungal and 1,3-β-D-glucan synthase inhibitory activities of caffeic and quinic acid derivatives.

Published Oct 1, 2010 · Chao-Mei Ma, T. Abe, T. Komiyama

Bioorganic & medicinal chemistry

Q2 SJR score

47

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1

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Abstract

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In Vitro Study

Study Snapshot

Caffeic and quinic acid derivatives with an H2N-orn-4-(octyloxy) aniline group show potent anti-fungal and inhibitory activities on fungal 1,3--glucan synthase, suggesting potential for novel anti-fungal agents with drug-like properties

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Synthesis, anti-fungal and 1,3-β-D-glucan synthase inhibitory activities of caffeic and quinic acid derivatives.

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