Dorota Czajkowska-Szczykowska, Izabella Jastrzebska, R. Santillán
Dec 9, 2014
Abstract The syntheses of four macrocyclic molecular rotors are described. The starting oxosteroids, 5β-androsterone, and 23-oxosarsasapogenin, were subjected to Grignard ethynylation followed by Sonogashira coupling with 1,4-diiodobenzene. The obtained acyclic dimers were further transformed into the corresponding 3-esters with terminal double bonds. These compounds were converted into the final products via an RCM protocol.