2,3,5,6-Tetrafluoroaniline was prepared from 2,3,5,6-tetrafluorobenzoic acid as raw material through a series of reactions including acyl chlorination,amidation and Hofmann degradation. Yield and purity of the product was75.6% and 98%,respectively. This is a promising industrial synthetic route.

This study demonstrates a promising industrial synthetic route for 2,3,5,6-tetrafluoroaniline, yielding 75.6% and 98% purity, with potential applications in pharmaceuticals and cosmetics.

Paper

Sythesis of 2,3,5,6-Tetrafluoroaniline

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