Paper
Tetrandrine cytotoxicity and its dual effect on oxidative stress-induced apoptosis through modulating cellular redox states in Neuro 2a mouse neuroblastoma cells.
Published Sep 13, 2002 · Quanri Jin, Chulhun Kang, Y. Soh
Life sciences
Q1 SJR score
62
Citations
4
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Tetrandrine has a dual effect on cytotoxicity and cytoprotection, regulating cellular redox states to either inhibit or promote cell death induced by oxidative stress in Neuro 2a mouse neuroblastoma cells.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
Anti-inflammatory effects of the partially purified extract of radix Stephaniae tetrandrae: comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions.
SPRST's myocardial protective effect is mediated by inhibiting neutrophil adhesion and transmigration, potentially through G protein modulation and preventing Mac-1 up-regulation in neutrophil activation.
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Tetrandrine inhibits nitric oxide production in vascular endothelial cells by blocking calcium release-activated calcium channels.
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Citations
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Co-loaded paclitaxel dimer prodrug and tetrandrine nanoparticles show potential in overcoming multidrug-resistant cancer by increasing drug penetration and causing more apoptosis in cancer cells.
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