Therapeutic effect of Moringa oleifera leaves on constipation mice based on pharmacodynamics and serum metabonomics.

doi:10.1016/j.jep.2021.114644

Paper

DOI: 10.1016/j.jep.2021.114644

Therapeutic effect of Moringa oleifera leaves on constipation mice based on pharmacodynamics and serum metabonomics.

Published Sep 14, 2021 · Caifeng Li, Zhiyong Li, Hongwei Wu

Journal of ethnopharmacology

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Abstract

Abstract removed due to Elsevier request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Study Snapshot

Key takeawayMoringa oleifera leaves have a long-lasting, mild laxative effect, increasing defecation volume and water content, potentially offering a fewer side effects treatment for constipation compared to other traditional Chinese medicines.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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References

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Metabolomics study on the therapeutic effect of the Chinese herb pair Fructus Aurantii Immaturus and Rhizoma Atractylodis Macrocephalae in constipated rats based on UPLC-Q/TOF-MS analysis.

Zhishi-Baizhu (ZSBZ) effectively treats slow transit constipation in rats, mainly through caffeine and vitamin B6 metabolism.

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Laxative metabolites from the leaves of Moringa oleifera.

Moringa oleifera leaves contain new flavonoids and alkaloids, including 1-octacosanol, which shows promising laxative activity against diphenoxylate-induced constipation in mice.

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Citations

DOI: 10.1155/2024/1270903

Moringa oleifera: Recent Insights for Its Biochemical and Medicinal Applications

Moringa oleifera (MO) has diverse medicinal and nutritional applications, including controlling various disorders and maintaining optimal health.

2024·7citations·Aaser M. Abdelazim et al.·Journal of Food Biochemistry

Journal of Food Biochemistry

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Moringa oleifera leaf alleviates functional constipation via regulating the gut microbiota and the enteric nervous system in mice

Moringa oleifera leaf alleviates functional constipation in mice by regulating gut microbiota and the enteric nervous system, improving intestinal barrier function and promoting defecation.

2023·2citations·Xiaoyu Gao et al.·Frontiers in Microbiology

Frontiers in Microbiology

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Barley Vinegar Relieves Loperamide-Induced Constipation in Mice via the Modulation of the Gut Microbiota and Serum Metabolism

Highland barley vinegar alleviates constipation in mice by regulating gut microbiota and lipid metabolism, preventing intestinal injury and improving bowel function.

2023·0citations·Yan Li et al.·Fermentation

Fermentation

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Hemp Seed Fermented by Aspergillus oryzae Attenuates Lipopolysaccharide-Stimulated Inflammatory Responses in N9 Microglial Cells

Fermented hemp seed, fermented by Aspergillus oryzae, effectively reduces neuroinflammation by suppressing reactive oxygen species production, inhibiting NF-B, MAPKs, and PI3K/Akt activation, and reducing inflammatory mediators and cytokines.

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Foods