Paper
THERAPEUTIC POTENTIAL OF OCIMUM SANCTUM IN PREVENTION AND TREATMENT OF CANCER AND EXPOSURE TO RADIATION: AN OVERVIEW
Published Apr 1, 2012 · B. R. Pandey, P. Verma, M. Bhalla
International Journal of Pharmaceutical Sciences and Drug Research
70
Citations
2
Influential Citations
Abstract
Extensive studies, experimental and clinical prove that Tulsi possess anti-stress/adatogenic, antioxidant, immunomodulator and anti-radiation properties which also may help it to play major role in prevention and treatment of cancer. As Tulsi has health benefitting effects by reducing stress and improving both cellular and humoral immunity, its role in prevention and treatment of cancer cases may be a new approach in therapy of cancer and in prevention of ill effects of radiation. Studies in biological models like fibrosarcoma cell culture, papilomas in the skin of albino mice, mice having sarcoma - 180 solid tumors etc. provide proof for its anticancer activity. As it has been shown that Tulsi exhibit anticancer activity in animal models, studies were carried out in human cancer in vivo like human cell fibrosarcoma and in vitro in human cervical cancer cell line (HeLa) and human laryngeal epithelial carcinoma cell line (HEp-2) and it was found effective. Thus, this review is a concise version of Tulsi’s anti-cancer effect. The aim is to stimulate research in this field, prevent and treat human carcinoma by initiating detailed studies in this field. It will be a novel agent, safe and effective for humans suffering with cancer in general and as a specific agent. The research work which is going on this direction is a proof of benefits by reducing toxicity of chemo and radio therapies and providing better and healthier life style by Tulsi. Therefore, it was worthwhile to review its anticancer properties to give an overview of its status to scientist both modern and ancient (Ayurvedic).
Tulsi has potential anti-cancer properties by reducing stress and improving immunity, offering a new approach in cancer therapy and radiation exposure prevention.
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