Thiol-mediated generation of nitric oxide accounts for the vasodilator action of furoxans.

doi:10.1016/0006-2952(92)90379-W

Paper

DOI: 10.1016/0006-2952(92)90379-W

Thiol-mediated generation of nitric oxide accounts for the vasodilator action of furoxans.

Published Sep 25, 1992 · M. Feelisch, Karl Schönafingeri, Hike Noack

Biochemical pharmacology

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144

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Highly Cited

Study Snapshot

Furoxans increase coronary flow by generating nitric oxide through chemical reaction with thiols and proteins, making them potential nitrovasodilators.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Emerging synthetic gasotransmitter-releasing strategies offer potential for controlled and sustained neurophysiological homeostasis restoration in neurological diseases.

2023·6citations·Rafat Ali et al.·Journal of controlled release : official journal of the Controlled Release Society

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Overview of the effects and mechanisms of NO and its donors on biofilms.

Nitric oxide (NO) shows potential in disrupting microbial biofilms in the food industry, improving bactericidal effect without drug resistance.

2023·3citations·Yanan Tian et al.·Critical reviews in food science and nutrition

Critical reviews in food science and nutrition

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Proteomics Studies Suggest That Nitric Oxide Donor Furoxans Inhibit In Vitro Vascular Smooth Muscle Cell Proliferation by Nitric Oxide-Independent Mechanisms

Furoxans, a nitric oxide donor, can inhibit smooth muscle cell proliferation in vitro through nitric oxide-independent mechanisms, making them potential antiatherosclerotic agents.

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Synthetic approaches and applications of an underprivileged 1,2,5‐oxadiazole moiety: A review

1,2,5-oxadiazole has potential applications in medicinal, material, and agriculture sciences, but has received little attention from researchers.

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Recent progress in synthesis and application of furoxan

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RSC Advances