M. Dolz-Planas, F. González-Rodriguez, R. Belda-Maximino
Sep 1, 1988
Journal of pharmaceutical sciences
An extensive study has been made of the thixotropic behavior of a microcrystalline cellulose-sodium carboxymethylcellulose gel (2% weight) and of its modification due to physical factors such as agitation time, duration of storage at rest, and temperature. An empirical function, giving thixotropic area variation rate as a function of agitation time, was obtained and found to be practically independent of storage time.