Paper
Thyroid Peroxidase Antibody (TPO) As a Predictor Of Radiation Induced Thyroid Dysfunction Among Nurses And Technicians Working In Mansoura Specialized Medical Hospital: Cross Sectional Study.
Published Feb 14, 2020 · Ahmed Albehairy, S. Fathy, Rania Bahriz
Endocrine, metabolic & immune disorders drug targets
5
Citations
0
Influential Citations
Abstract
OBJECTIVE Evaluation of the role of Thyroid peroxidase antibody as a predictor for thyroid dysfunction among nurses and technicians in the radiology department in Mansoura Specialized Medical hospital (MSMH). SUBJECTS AND METHODS Subjects were Nurses and technicians who are working in (MSMH) with persistent daily duty in the last 3 years and fulfilling the inclusion and exclusion criteria. All subjects included in the study were recruited in one month and divided into two groups; Group 1: 50 subjects who were working in radiology, coronary angiography and ERCP unit, Radiation -exposed group. Group2:33subjects who were working in In-patient departments and in out- patient clinics and not exposed to any type of radiation. Non fasting blood sample was taken from all enrolled subjects for measurement of TSH and Anti-TPO. RESULTS TPO was positively and significantly correlated to age, TSH, Duration of radiology/ y (r=0.388, 0.364, 0.342respectively) p value <0.05. Roc curve was done to detect the sensitivity and specificity of TSH in Relation to TPO the revealed a cutoff value of TSH > 1.69 with Sensitivity, Specificity. PPV, NPV and accuracy at cutoff >1.69 were (70.6%, 51.5%, 42.8%, 77.3% and 58%). CONCLUSION Already working personnel with positive anti TPO and their TSH levels are more than 1.69 associated with symptoms of hypothyroidism, a trial of treatment is mandatory to relief symptoms.
Observational StudyThyroid peroxidase antibody (TPO) is a predictor for thyroid dysfunction in radiology department workers, with TSH levels over 1.69 being a significant risk factor for hypothyroidism.
Full text analysis coming soon...