Paper
Vaginal Yeast Infection
Published Jan 1, 2019 · M. Blaganje, M. Barbič
Current Bladder Dysfunction Reports
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Influential Citations
Abstract
Purpose of ReviewThis review includes a detailed overview of the vaginal yeast infection based on current literature available, addressing etiology, epidemiology, risk factors, and pathophysiology, as well as clinical presentation, burden, diagnostic, and treatment strategies.Recent FindingsThere are multiple meta-analyses, systematic reviews, randomized control trials, and critical reviews recently published that have advanced the understanding of pathophysiology and answered questions regarding global burden, prevention, and treatment in a systematic way.SummaryIn the recent years, important work has been made to better understand the pathophysiology and global burden behind the vaginal yeast infection. Diagnostic criteria were proposed for chronic vulvovaginal candidiasis. While fluconazole resistance has been making maintenance suppressive therapy of recurrent vulvovaginal candidiasis difficult and probiotics do not seem to be very effective, significant improvements and advances in the area of antifungal therapeutic innovation research have been made and further results of vaccine trials are pending. There is a need for well-designed RCTs in evidence-based treatment development and research.
Systematic ReviewRecent years have advanced understanding of vaginal yeast infection pathophysiology and global burden, with significant improvements in antifungal therapeutic innovation research.
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