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These studies suggest that maintaining a fasting blood glucose level of 108 mg/dL can improve blood glucose control and reduce microvascular complications in type 2 diabetes patients.
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Fasting blood glucose levels are a critical measure in managing non-insulin-dependent diabetes, also known as type 2 diabetes. A fasting blood glucose level of 108 mg/dL (6 mmol/L) is often used as a target for effective diabetes control. This target is significant because it helps in reducing the risk of complications associated with diabetes.
A study conducted across ten general practices investigated the feasibility of controlling non-insulin-dependent diabetes by aiming for a fasting blood glucose concentration of less than 108 mg/dL. The results were promising, showing a significant improvement in blood glucose levels among patients. Initially, only 26% of patients had fasting blood glucose levels below 108 mg/dL, but this number increased to 59% after one year of implementing the control method.
The study also reported a significant reduction in the mean fasting blood glucose concentration from 148 mg/dL to 113 mg/dL within three months, which slightly increased to 126 mg/dL after one year but remained significantly lower than the initial levels. Additionally, the mean hemoglobin A1c levels, which indicate long-term blood glucose control, were also significantly reduced.
The study highlighted that assessing control through four fasting blood glucose determinations per year is less expensive than regular urine tests and may improve overall blood glucose control. Different practices adopted various methods for implementing this control, with some preferring special clinics for fasting blood glucose measurements and others achieving good results through practical nurses under the supervision of general practitioners.
The United Kingdom Prospective Diabetes Study (UKPDS) further supports the importance of maintaining a fasting blood glucose level of 108 mg/dL. The study demonstrated that intensive treatment aimed at achieving this target significantly reduces the microvascular complications of type 2 diabetes mellitus. This finding underscores the critical role of stringent blood glucose control in preventing long-term complications in diabetic patients.
Maintaining a fasting blood glucose level of 108 mg/dL is a feasible and effective strategy for managing type 2 diabetes. Both general practice care and large-scale studies like the UKPDS have shown that this target can significantly improve blood glucose control and reduce complications. Implementing regular fasting blood glucose measurements and adopting cost-effective methods can enhance diabetes management and patient outcomes.
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