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These studies suggest that mouthrinses can effectively treat oral halitosis, reduce dental caries, plaque, and gingivitis, but some may have side effects or erosive potential on dentin.
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ACT mouthrinse is a popular oral hygiene product known for its fluoride content, which is designed to prevent dental caries and improve overall oral health. This article synthesizes research findings on the clinical effects, safety, and potential side effects of ACT mouthrinse and other similar products.
Fluoride mouthrinses, including ACT, have been extensively studied for their role in preventing dental caries in children and adolescents. A comprehensive review of 36 studies involving 14,600 children demonstrated that regular use of fluoride mouthrinse significantly reduces caries increment by 26% compared to placebo or no treatment. This reduction was consistent regardless of baseline caries severity, fluoride concentration, or rinsing frequency.
Mouthrinses containing chlorhexidine, cetylpyridinium chloride, and zinc-lactate have shown significant efficacy in reducing oral halitosis. A study involving 40 volunteers found that such a formulation led to a significant reduction in organoleptic scores and volatile sulfur compounds (VSC) levels, which are primary indicators of bad breath. Another study with 174 participants confirmed these findings, showing that mouthrinses with similar active ingredients effectively reduce oral malodour over a three-week period.
Histatin-based mouthrinses have been evaluated for their safety and effectiveness in reducing plaque and gingivitis. A study with 159 subjects found that a 0.01% P-113 histatin mouthrinse significantly reduced plaque and gingivitis without adverse effects on periodontal flora. This suggests that histatin-containing mouthrinses can be a safe and effective option for managing gingivitis.
A six-month clinical trial comparing chlorhexidine and essential oil mouthrinses found both to be effective in reducing plaque and gingivitis. However, chlorhexidine was associated with more side effects, such as increased calculus and tooth staining, which may affect patient compliance. This indicates that while both types of mouthrinses are effective, essential oil mouthrinses may be preferable for long-term use due to fewer side effects.
The erosive potential of mouthrinses on enamel and dentin has been a concern. An in vitro study measured the pH and titratable acidity of various mouthrinses, including ACT Total Care, and found significant differences in their erosive potential. Mouthrinses with lower pH values and higher titratable acidity, such as Listerine Ultraclean, showed a higher potential for dentin erosion. This highlights the importance of considering the erosive potential when selecting a mouthrinse.
ACT mouthrinse and other fluoride-containing mouthrinses are effective in preventing dental caries, particularly in children and adolescents. Formulations containing chlorhexidine, cetylpyridinium chloride, and zinc-lactate are effective in reducing oral halitosis. Histatin-based mouthrinses offer a safe option for managing gingivitis, while essential oil mouthrinses provide a balance between efficacy and side effects. However, the potential erosive effects on enamel and dentin should be considered when choosing a mouthrinse. Overall, ACT mouthrinse remains a valuable tool in maintaining oral health, with its benefits outweighing potential drawbacks when used appropriately.
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