Searched over 200M research papers for "addiction"
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These studies suggest that addiction is a chronic brain disease involving genetic, neuroplastic, and environmental factors, characterized by changes in reward, self-control, and affect pathways, and requiring comprehensive treatment approaches.
20 papers analyzed
Addiction is a chronic, relapsing disorder characterized by compulsive drug seeking and use despite harmful consequences. It involves complex interactions between genetic, neurobiological, and environmental factors. Understanding the mechanisms underlying addiction is crucial for developing effective prevention and treatment strategies.
Genetic and Environmental Factors:
Neurocircuitry and Brain Regions:
Dopamine's Role:
Neuroplasticity and Synaptic Changes:
Behavioral and Social Context:
Inhibitory Control Dysfunction:
Addiction is a multifaceted disorder involving genetic, neurobiological, and environmental factors. Key brain circuits and neurotransmitter systems, particularly those involving dopamine, play crucial roles in the development and persistence of addictive behaviors. Effective treatment strategies must address the biological, behavioral, and social-context aspects of addiction to mitigate its impact on individuals and society.
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