Allergy sinus
Pro Research Analysisby 
Searched over 200M research papers for "allergy sinus"
Allergy and Sinusitis: Understanding the Connection
Prevalence of Allergy in Sinusitis Patients
Allergy is a significant factor in the development and exacerbation of sinusitis. Studies have shown that a notable percentage of patients with acute maxillary sinusitis also have allergies. In a study involving 224 patients with acute maxillary sinusitis, 25% were found to have allergies, with an additional 6.5% considered probable cases of allergy. This is significantly higher compared to the control group, indicating a strong association between allergy and sinusitis1.
Diagnostic Tools for Sinusitis in Allergic Patients
Modern diagnostic tools such as nasal endoscopy and computed tomographic (CT) scanning are essential for evaluating patients with acute and chronic sinusitis. These tools help in identifying areas of inflammation and pathological drainage, which are common in allergic patients. Nasal endoscopy provides a detailed view of the nasal passages, while CT scans reveal the fine structures and extent of the disease, aiding in accurate diagnosis and management2.
Impact of Allergy on Sinusitis in Different Age Groups
Research indicates that the prevalence of sinusitis is not significantly different between allergic and non-allergic individuals. However, age plays a crucial role in the extent of sinus disease. In studies comparing allergic and non-allergic children and adults, the prevalence of sinusitis was similar across both groups, suggesting that factors other than allergy, such as age, may influence the severity of sinus involvement3.
Allergic Rhinitis and Sinus Inflammation
Allergic rhinitis can lead to chronic inflammation of the sinuses. Nasal allergen challenges have been shown to cause significant increases in inflammatory markers in the maxillary sinuses, indicating that allergic reactions in the nasal passages can extend to the sinuses. This inflammation is likely mediated by a neural reflex or systemic allergic response, contributing to the development of rhinosinusitis in allergic individuals4.
Sinus Disease in Children with Respiratory Allergies
Children with respiratory allergies often experience significant sinus involvement, which can exacerbate their overall allergic condition. Controlling sinus disease in these children can lead to better management of their respiratory allergies. This highlights the importance of addressing sinus issues in pediatric patients with allergies to improve their overall health outcomes5.
Chronic Hyperplastic Eosinophilic Sinusitis (CHES) and Allergy
Chronic hyperplastic eosinophilic sinusitis (CHES) is characterized by eosinophil infiltration and is often associated with aeroallergen sensitization. Although the direct causality between allergen exposure and CHES is unclear, systemic allergic inflammation plays a significant role. Treatments targeting allergic mediators, such as leukotriene modifiers and corticosteroids, have shown promise in managing this condition6.
Allergy as a Contributory Factor in Sinusitis
Allergic rhinitis and sinusitis frequently coexist, with studies documenting their presence in the same patient 25% to 70% of the time. This prevalence is higher than that of allergic rhinitis alone in the general population, underscoring the importance of allergy as a contributory factor in sinusitis. Younger children are particularly at risk due to their smaller anatomical structures and higher exposure to allergens7.
Surgical Interventions and Allergy Management
Functional endoscopic sinus surgery (FESS) is often performed in patients with chronic rhinosinusitis refractory to medical therapy. A significant proportion of these patients have underlying allergies, particularly to perennial allergens like house dust mites. Identifying and managing these allergies through avoidance, pharmacotherapy, and immunotherapy can help prevent recurrent and chronic sinusitis9.
Allergic Fungal Sinusitis: Diagnosis and Treatment
Allergic fungal sinusitis (AFS) is a noninvasive condition that requires specific diagnostic criteria, including a history of inhalant mold allergies, nasal polyposis, and characteristic CT findings. Differentiating AFS from other forms of sinusitis is crucial for appropriate treatment, which often involves managing the underlying allergic response10.
Conclusion
Allergy plays a significant role in the development and exacerbation of sinusitis. Accurate diagnosis using advanced tools, understanding the impact of age and respiratory allergies, and targeted treatments can significantly improve outcomes for patients with allergic sinusitis. Addressing the underlying allergic conditions is essential for effective management and prevention of recurrent sinus issues.
Sources and full results
Most relevant research papers on this topic
Allergy in patients with acute maxillary sinusitis
Allergy is found in 25% of patients with acute maxillary sinusitis, but the frequency is lower than previously reported on chronic sinusitis.
Highly CitedDiagnosis and management of sinusitis in the allergic patient
Nasal endoscopy and computed tomography scanning are essential for diagnosing and managing sinusitis in allergic patients.
Sinusitis in allergic patients.
Allergy does not determine the prevalence or extent of sinusitis, but age is a major factor in the development of this disease.
Observational StudyNasal challenge with allergen leads to maxillary sinus inflammation.
Nasal allergen challenge leads to maxillary sinus inflammation, which may contribute to the development of chronic rhinosinusitis in allergic subjects.
RCTHighly CitedSinus disease in children with respiratory allergy.
Sinus disease is prevalent in children with respiratory allergy, often adding to the morbidity rate and making allergic respiratory treatment easier to control.
Highly CitedThe role of allergy in sinusitis in children.
Allergy is an important associated factor in sinusitis in children, with younger children at higher risk due to small anatomic structures, more frequent viral infections, and increased exposure to indoor allergens and irritants.
Highly CitedThe effect of nasal and sinus surgery upon the manifestations of allergy.
Nasal and sinus surgery may not significantly affect allergy manifestations, but rather depends on a patient's specific allergy symptoms and the surgeon's experience.
Chronic rhinosinusitis: Allergy and sinus computed tomography relationships
Perennial allergens, particularly house dust mite, play a significant role in the development of chronic rhinosinusitis, and early identification and treatment may help prevent recurrent and chronic episodes.
Highly CitedDiagnosis of Allergic Fungal Sinusitis
The diagnosis of allergic fungal sinusitis should be established by meeting the following criteria: type I hypersensitivity, nasal polyposis, characteristic computed tomography signs, eosinophilic mucus without fungal invasion, and positive fungal stain during surgery.
Highly Cited