How is amoebiasis treated?

Introduction

Amoebiasis, caused by the protozoan Entamoeba histolytica, is a significant global health concern, particularly in developing countries. Treatment strategies for this parasitic infection are crucial for reducing morbidity and mortality associated with the disease.

Key Insights from Research Papers

Nitazoxanide has been shown to be effective in treating intestinal amoebiasis and eliminating E. histolytica colonization in the intestinal tract, with a high percentage of patients responding positively to the treatment.
Emetine bismuth iodide has been identified as a highly satisfactory drug for treating intestinal amoebiasis, with a low relapse rate observed among patients.
Metronidazole is recognized as a potent systemic amoebicide with minimal toxicity, providing rapid symptomatic relief and a high parasitological cure rate for amoebic dysentery and liver abscesses.
The use of diloxanide furoate, also known as Furamide, has been reported to yield very good results in treating asymptomatic intestinal amoebiasis.
Probiotics have been suggested as a complementary treatment for amoebiasis, with potential to serve as an alternative to traditional anti-amoebic compounds that may have side effects.
Other treatments such as tiberal (Roche) and metronidazole have been found to achieve a 100% cure rate in intestinal amoebiasis patients, without observed side effects or relapses.

Conclusion

The treatment of amoebiasis involves a range of anti-amoebic medications, with metronidazole standing out as a particularly effective and low-toxicity option. Nitazoxanide and emetine bismuth iodide are also effective, particularly for intestinal infections. Diloxanide furoate is recommended for asymptomatic cases, while probiotics are emerging as a potential complementary therapy. The overall goal of treatment is to alleviate symptoms, eradicate the infection, and prevent relapses.

How is amoebiasis treated?

Summary

Introduction

Key Insights from Research Papers

Conclusion

Sources and full results

Nitazoxanide in the treatment of amoebiasis.

Nitazoxanide effectively treats invasive intestinal amoebiasis and eliminates E. histolytica colonization in the intestinal tract, with all patients responding to therapy.

Symposium on the treatment of human amoebiasis. II. The treatment of intestinal amoebiasis with emetine bismuth iodide, glaucarubin, dichloroacet-hydroxy-methylanilide, camoform and various antibiotics.

Emetine bismuth iodide is the most satisfactory drug currently available for treating intestinal amoebiasis, with a relapse rate of 3% compared to glaucarubin and dichloroacet-hydroxy-methylanilide.

Averting transmission: A pivotal target to manage amoebiasis.

Targeting essential metabolic processes and associated biomolecules using CRISPR-Cas9 system can effectively prevent amoebiasis transmission and manage the disease.

Intestinal amoebiasis in a patient with acute graft‐versus‐host disease after allogeneic bone marrow transplantation successfully treated by metronidazole

Intestinal amoebiasis can be unexpectedly revealed by colonoscopy after allogeneic bone marrow transplantation, but metronidazole effectively treats it.

Treatment of Amoebiasis

Metronidazole is a highly effective, non-toxic treatment for amoebic dysentery, with tetracycline and emetine reinforcing the treatment.

Entamide and furamide in the treatment of amoebic infection in Nekuru, Kenya.

Entamide and furamide are effective and safe treatments for amoebic infection in Nakuru, Kenya, with no toxic effects or relapses observed.

Amoebiasis and probiotics: perspectives on complementary treatment

Probiotics show promise as an alternative and effective treatment for amoebiasis patients, offering a promising alternative to potentially harmful medications like metronidazole.

Case report: hepatobronchial fistula complicating amoebiasis, treated by percutaneous catheter drainage.

Percutaneous catheter drainage effectively resolves bronchohepatic fistulas in hepatic amoebiasis patients, avoiding open surgery.

The treatment of amoebiasis with lodoxyquinolin sulphonic acid

Iodoxyquinolin sulphonic acid (anayodin) is a useful drug for treating intestinal amoebiasis, effectively stopping severe symptoms and curing acute and carrier cases, but not all cases.

Tiberal (Ro 7-0207-Roche) in the treatment of intestinal amoebiasis--Part II.

Tiberal and metronidazole effectively treat intestinal amoebiasis with no side effects or toxicity, and both drugs show no signs of relapse after discharge.

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