Ashwagandha supplementation significantly reduces anxiety and stress levels, but further high-quality studies are needed to confirm its clinical efficacy.

Does Ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? A systematic review and meta‐analysis of randomized controlled trials

Ashwagandha treatment significantly improves anxiety and stress scores compared to placebo in most studies, but current evidence is limited by study methods and potential bias.

An alternative treatment for anxiety: a systematic review of human trial results reported for the Ayurvedic herb ashwagandha (Withania somnifera).

Ashwagandha root and leaf extracts show promising anti-stress, anti-anxiety, and depression effects, but more research is needed on optimal preparation and dosage for treating neuropsychiatric conditions.

Effects of Withania somnifera (Ashwagandha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia

Ashwagandha (ASW) is a well-tolerated and well-tolerated herbal treatment for anxiety disorders, with potential benefits comparable to those of lorazepam and without the disadvantages of conventional drugs.

Ashwagandha for anxiety disorders

A high-concentration full-spectrum Ashwagandha root extract safely and effectively reduces stress and anxiety in adults, improving their quality of life.

A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults

Ashwagandha root extract with 2.5% withanolides effectively reduces stress and anxiety by increasing serotonin and decreasing cortisol in healthy individuals with mild to moderate symptoms.

A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study

Ashwagandha shows potential in alleviating stress and anxiety symptoms, but more robust and adequately-powered research is needed to confirm its effectiveness across various mental and physical conditions.

Ashwagandha (Withania somnifera) for the treatment and enhancement of mental and physical conditions: A systematic review of human trials

Ashwagandha shows potential in reducing stress, improving cognition, and enhancing exercise capacity in healthy adults, but more large-scale, methodologically stringent clinical trials are needed for confident recommendations.

Potential clinical applications of Ashwagandha (Withania somnifera) in medicine and neuropsychiatry

Ashwagandha root extract shows efficacy and safety in treating insomnia, anxiety, and reducing stress, but further research is needed to confirm its role in these conditions.

Efficacy and safety of ashwagandha root extract in the treatment of insomnia, anxiety and reducing stress – literature review

Ashwagandha supplementation significantly reduces stress and anxiety in stressed adults, potentially due to its moderating effect on the hypothalamus-pituitary-adrenal axis.

An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract

Ashwagandha root extract effectively reduces stress and anxiety in healthy adults, with higher doses improving sleep quality.

Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study

Ashwagandha sustained-release formulation (AshwaSR) shows potential in managing stress and stress-related symptoms by inhibiting pro-inflammatory cytokines and superoxide production.

Efficacy and Anti-Inflammatory Activity of Ashwagandha Sustained-Release Formulation on Depression and Anxiety Induced by Chronic Unpredictable Stress: in vivo and in vitro Studies

Ashwagandha root extract, at 300 mg twice daily, improves sleep quality and sleep onset latency in patients with insomnia.

Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study

Ashwagandha supplementation for college students improved their perceived well-being by supporting sustained energy, mental clarity, and enhanced sleep quality.

The Perceived Impact of Ashwagandha on Stress, Sleep Quality, Energy, and Mental Clarity for College Students: Qualitative Analysis of a Double-Blind Randomized Control Trial.

Ashwagandha shows potential as a neuroprotective agent in various brain disorders, but further study is needed to confirm its mechanistic pathways and promote it as a promising drug candidate.

Ashwagandha in brain disorders: A review of recent developments.

Ashwagandha shows anxiolytic effect and is comparable to Paroxetine in treating generalized anxiety disorder, with potential benefits for patients with underlying anxiety disorders.

A CLINICAL STUDY TO COMPARE THE EFFICACY OF PAROXETINE VERSUS ASHWAGANDHA IN PATIENTS SUFFERING FROM GENERALIZED ANXIETY DISORDER.

Ashwagandha standardized extract shows potential in treating depression and anxiety symptoms in schizophrenia patients.

Effects of a standardized extract of Withania somnifera (Ashwagandha) on depression and anxiety symptoms in persons with schizophrenia participating in a randomized, placebo-controlled clinical trial.

Ashwagandha, a traditional treatment, may be beneficial in treating depression due to its components, withanolides and alkaloides, which also improve anxiety and stress.

Can Traditional Treatment Such as Ashwagandha Be Beneficial in Treating Depression?

Ashwagandha root extract can effectively aid in body weight management and reduce stress in adults under chronic stress, while being safe and tolerable.

Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract

Ashwagandha root extract improves sleep quality and helps manage insomnia, with more significant improvements in insomnia patients.

Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.

These studies suggest that ashwagandha is effective in reducing anxiety and stress, but further high-quality research is needed to confirm its clinical efficacy and optimal usage.