Ashwagandha root extract consumption for 8 weeks was safe in both males and females, with no reported adverse events.

Safety of Ashwagandha Root Extract: A Randomized, Placebo-Controlled, Study in Healthy Volunteers.

Ashwagandha root extract may effectively normalize thyroid indices in subclinical hypothyroid patients, with few mild and temporary adverse effects.

Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial.

Ashwagandha extract has a small but significant effect on improving sleep in adults, with more pronounced effects in insomnia patients.

Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis

Ashwagandha extract supplementation for six weeks significantly improved overall sleep quality and quality of life in healthy adults without causing adverse events.

A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.

A high-concentration full-spectrum Ashwagandha root extract safely and effectively reduces stress and anxiety in adults, improving their quality of life.

A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults

Ashwagandha shows potential as a neuroprotective agent in various brain disorders, but further study is needed to confirm its mechanistic pathways and promote it as a promising drug candidate.

Ashwagandha in brain disorders: A review of recent developments.

Ashwagandha shows potential therapeutic effects and is a safe compound with little or no associated toxicity.

Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.

Ashwagandha root extract may improve memory and cognitive functions in adults with mild cognitive impairment, enhancing executive function, attention, and information processing speed.

Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions

Ashwagandha root extract effectively enhances cardiorespiratory endurance and improves quality of life in healthy athletic adults without causing adverse events.

A double-blind, randomized, placebo-controlled trial on the effect of Ashwagandha (Withania somnifera Dunal.) root extract in improving cardiorespiratory endurance and recovery in healthy athletic adults.

Ashwagandha root extract effectively improves quality of life, sleep quality, and mental alertness in elderly individuals, with good tolerability and reported as safe and beneficial.

Efficacy and Tolerability of Ashwagandha Root Extract in the Elderly for Improvement of General Well-being and Sleep: A Prospective, Randomized, Double-blind, Placebo-controlled Study

Ashwagandha can effectively manage stress and improve sleep quality in college students in as little as 30 days, with lower food cravings observed over time.

The Impact of Ashwagandha on Stress, Sleep Quality, and Food Cravings in College Students: Quantitative Analysis of a Double-Blind Randomized Control Trial.

Ashwagandha shows potential as a chemotherapeutic agent against various types of breast cancer, with potential benefits for ER/PR positive and triple-negative breast cancers.

Keeping abreast about Ashwagandha in breast cancer.

W-ferinAmax ashwagandha (WFA) is a safe, standardized extract from the whole plant of Withania somnifera, with minimal heavy metals and pathogenic microbes, making it suitable for human consumption.

Chemical, microbial and safety profiling of a standardized Withania somnifera (Ashwagandha) extract and Withaferin A, a potent novel phytotherapeutic of the millennium

Ashwagandha root extract supplementation for eight weeks effectively improves muscle strength, growth, endurance, and recovery in both male and female participants.

Effects of Ashwagandha ( Withania somnifera) standardized root extract on physical endurance and VO 2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study

Ashwagandha root and leaf extracts show promising anti-stress, anti-anxiety, and depression effects, but more research is needed on optimal preparation and dosage for treating neuropsychiatric conditions.

Effects of Withania somnifera (Ashwagandha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia

Ashwagandha root extract shows potential in treating insomnia, stress-related disorders, cognitive functions, endocrine diseases, and enhancing muscle strength and recovery in healthy adults.

Potential clinical usage of ashwagandha root extract: A review

Ashwagandha root extract capsules, taken daily for 90 days, significantly improved memory, focus, psychological well-being, and sleep quality in stressed adults without causing adverse events.

Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study

Ashwagandha shows potential in alleviating stress and anxiety symptoms, but more robust and adequately-powered research is needed to confirm its effectiveness across various mental and physical conditions.

Ashwagandha (Withania somnifera) for the treatment and enhancement of mental and physical conditions: A systematic review of human trials

Ashwagandha root extract shows potential in reducing hepatic and cognitive deficits in a thioacetamide-induced rat model of hepatic encephalopathy, with potential benefits for treating liver diseases.

Ashwagandha (Withania somnifera) root extract attenuates hepatic and cognitive deficits in thioacetamide-induced rat model of hepatic encephalopathy via induction of Nrf2/HO-1 and mitigation of NF-kB/MAPK signaling pathways.

Ashwagandha intake for 8 weeks increased levels of DHEA-S and testosterone in overweight men, but did not significantly affect cortisol, estradiol, fatigue, vigor, or sexual well-being.

A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha (Withania somnifera) in Aging, Overweight Males

These studies suggest Ashwagandha is generally safe with few mild and temporary adverse effects.