Ashwagandha side effects heart
Pro Research Analysisby
Searched over 200M research papers
Consensus Meter
Ashwagandha Side Effects on the Heart
Introduction to Ashwagandha and Cardiovascular Health
Ashwagandha (Withania somnifera) is a well-known herb in traditional Ayurveda, reputed for its adaptogenic properties and its ability to enhance overall well-being. However, its effects on cardiovascular health, particularly potential side effects on the heart, are of significant interest.
Cardioprotective Properties of Ashwagandha
Adaptogenic and Cardioprotective Actions
Research has demonstrated that ashwagandha possesses notable cardioprotective properties. In animal studies, ashwagandha increased the relative heart weight and glycogen content in the myocardium and liver, indicating enhanced cardiac function and energy storage. Additionally, it improved the resistance of frog heart muscle to toxic substances, suggesting a protective effect on heart muscle contractility. These findings highlight ashwagandha's potential in supporting heart health under stress conditions.
Enhanced Cardiorespiratory Endurance
In human studies, ashwagandha has been shown to significantly improve cardiorespiratory endurance. A double-blind, randomized, placebo-controlled trial involving healthy athletic adults revealed that ashwagandha supplementation led to a significant increase in maximum aerobic capacity (VO2 max) and improved recovery from physical exertion. These improvements suggest that ashwagandha can enhance cardiovascular performance and resilience in physically active individuals.
Potential Side Effects on the Heart
Catecholamine Levels and Heart Rate Variability
While ashwagandha is generally considered safe, some studies have noted potential side effects related to heart function. High doses of ashwagandha have been associated with increased catecholamine content in the heart and aortic tissues, which could be unfavorable for individuals with certain cardiovascular conditions. Additionally, in a study on adults experiencing high stress and fatigue, ashwagandha supplementation was linked to a significant increase in heart rate variability, indicating an impact on the autonomic nervous system. This effect could be beneficial or detrimental depending on the individual's baseline heart health.
Coagulation Time and Anticoagulant Properties
Another aspect to consider is ashwagandha's effect on blood coagulation. Research has shown that ashwagandha treatment can significantly increase coagulation time, which normalizes after cessation of treatment. This anticoagulant property might be beneficial in preventing blood clots but could pose risks for individuals with bleeding disorders or those on anticoagulant medications.
Conclusion
Ashwagandha exhibits several cardioprotective and adaptogenic properties that can enhance cardiovascular health and performance. However, potential side effects, such as increased catecholamine levels and changes in heart rate variability, warrant caution, especially in individuals with pre-existing heart conditions. As with any supplement, it is crucial to consult with a healthcare provider before starting ashwagandha, particularly for those with cardiovascular concerns.
Sources and full results
Most relevant research papers on this topic