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Some studies suggest probiotic foods are more effective than supplements for promoting health and preventing diseases, while other studies highlight the benefits of probiotic supplements for immune response, gut health, and mental flexibility.
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Probiotics, beneficial live bacteria, can be delivered through foods or supplements. Both methods have shown efficacy in promoting health, but there is a preference for probiotic foods over supplements for general public health. This preference is based on the broader range of health benefits observed with probiotic foods, although no definitive clinical evidence favors one over the other.
Probiotic supplements have been shown to offer several health benefits in healthy adults. These include transient improvements in gut microbiota, enhanced immune responses, better stool consistency, improved bowel movements, and increased vaginal lactobacilli concentration. However, the evidence does not support long-term changes in gut microbiota or improvements in blood lipid profiles.
Probiotics can be particularly beneficial for individuals with lactose intolerance. Studies have demonstrated that certain probiotic strains in fermented and unfermented milk products can alleviate symptoms of lactose intolerance, improving overall intestinal health and immune responses.
In older adults, probiotics have been found to improve cognitive function and mood. A study involving Bifidobacterium bifidum BGN4 and Bifidobacterium longum BORI showed significant improvements in mental flexibility, stress reduction, and increased serum brain-derived neurotrophic factor (BDNF) levels. These changes were associated with a reduction in inflammation-causing gut bacteria.
Despite the popularity of probiotics, there are conflicting clinical results regarding their efficacy. The effectiveness of probiotics can vary based on strain, formulation, and individual responses. Large-scale, randomized studies are needed to clarify the specific health benefits and safety of probiotics for different populations.
Probiotics are also used in poultry nutrition to promote growth, improve nutrient utilization, and enhance gut health. They serve as a potential alternative to antibiotics, modifying intestinal microbiota, stimulating the immune system, and preventing pathogen colonization.
For patients with end-stage renal disease (ESRD), probiotics, prebiotics, and synbiotics offer different benefits. Probiotics are particularly effective in alleviating gastrointestinal symptoms, while prebiotics and synbiotics are more effective in reducing inflammatory markers and uremic toxins.
Choosing the best probiotic depends on individual health needs and conditions. Probiotic foods are generally preferred for overall public health, while supplements can offer specific benefits for gut health, immune response, and cognitive function. For those with lactose intolerance or ESRD, targeted probiotic strains can provide significant relief and health improvements. Further research is needed to fully understand the long-term benefits and optimal use of probiotics.
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