Blood sugar 139
Pro Research Analysisby 
Searched over 200M research papers
Blood Sugar Levels and Cardiometabolic Risk
Borderline Diabetes and Coronary Artery Disease
Prevalence and Prognostic Significance
Borderline diabetes, defined by fasting blood sugar levels between 126 to 139 mg/dl, has significant implications for patients with coronary artery disease (CAD). Research indicates that both undiagnosed and newly diagnosed borderline diabetes are associated with an unfavorable metabolic profile, which can complicate the management of CAD. Over a 7.7-year follow-up period, patients with borderline diabetes exhibited a tendency towards higher mortality rates compared to their non-diabetic counterparts, although this trend did not reach statistical significance. However, a significant increase in long-term mortality was observed among those with undiagnosed diabetes.
Dietary Sugars and Cardiometabolic Risk Factors
Impact on Blood Pressure and Lipids
Dietary sugars have been implicated in the development of various cardiometabolic risk factors, including elevated blood pressure and altered lipid profiles. A systematic review and meta-analysis of randomized controlled trials found that higher sugar intake significantly raised triglyceride levels, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol. Specifically, the mean differences (MD) for these lipid outcomes were 0.11 mmol/L for triglycerides, 0.16 mmol/L for total cholesterol, 0.12 mmol/L for LDL cholesterol, and 0.02 mmol/L for HDL cholesterol.
Blood Pressure Effects
The effect of sugar intake on blood pressure was also notable, particularly in trials lasting eight weeks or longer. The mean differences for systolic and diastolic blood pressure were 6.9 mm Hg and 5.6 mm Hg, respectively. These findings suggest that the relationship between dietary sugars and blood pressure is independent of the effects of sugars on body weight, highlighting the direct impact of sugar consumption on cardiovascular health.
Conclusion
In summary, borderline diabetes with fasting blood sugar levels between 126 to 139 mg/dl poses a significant risk for patients with coronary artery disease, potentially leading to higher long-term mortality rates. Additionally, high dietary sugar intake is associated with adverse changes in blood pressure and lipid profiles, further exacerbating cardiometabolic risks. These findings underscore the importance of early detection and management of borderline diabetes and the need for dietary modifications to mitigate cardiometabolic risks.
Sources and full results
Most relevant research papers on this topic