Brand name of valsartan
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Brand Name of Valsartan
Introduction to Valsartan
Valsartan is a medication primarily used to treat high blood pressure, congestive heart failure, and to improve survival chances after a heart attack. It functions as an angiotensin II receptor antagonist, specifically targeting the type I (AT1) angiotensin receptor .
Common Brand Names of Valsartan
Diovan®
One of the most well-known brand names for valsartan is Diovan®, which is produced by Novartis. Diovan® has been extensively studied and is often used as a reference formulation in bioequivalence studies .
Tareg®
Another brand name for valsartan is Tareg®, also produced by Novartis. Tareg® is frequently used as a reference product in bioequivalence studies to compare the pharmacokinetic properties of other valsartan formulations.
Valzan®
Valzan® is a generic formulation of valsartan that has been compared to Diovan® in bioequivalence studies. Research has shown that Valzan® exhibits a pharmacokinetic profile comparable to Diovan®, making it a viable alternative.
Bioequivalence Studies
Algerian Study
A study conducted in Algeria compared the bioavailability of two brands of valsartan 80 mg tablets, using Tareg® as the reference product. The study concluded that the test formulation was not bioequivalent to Tareg® under fasting conditions.
Bangladeshi Study
In Bangladesh, a comparative bioequivalence study evaluated the physicochemical properties and dissolution profiles of different valsartan brands. The study found that all tested brands met the required specifications, indicating that any of the brands could be used interchangeably based on economic conditions.
Indian Study
A study in India compared the pharmacokinetic properties of two branded generic valsartan formulations with a branded innovator product. The study found that one of the test formulations was bioequivalent to the reference product, while the other was not.
Valzan® vs. Diovan®
A study comparing Valzan® and Diovan® found no significant differences in their pharmacokinetic parameters, concluding that Valzan® is well-formulated and bioequivalent to Diovan®.
Conclusion
Valsartan is marketed under several brand names, including Diovan®, Tareg®, and Valzan®. Bioequivalence studies have shown that while some generic formulations are comparable to the reference brands, others may not meet the bioequivalence criteria. Therefore, it is essential to consider these studies when choosing a valsartan brand for treatment.
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