Searched over 200M research papers
10 papers analyzed
These studies suggest that calcium supplement tablets are effective in improving nutrient intake, bone mineral density, and preventing certain conditions like osteoporosis and preterm delivery, but excessive use may lead to mineral deficiencies.
19 papers analyzed
Calcium supplements are widely used to prevent and treat various health conditions, including osteoporosis, hypertension, and potentially colon cancer. They are particularly beneficial when dietary calcium intake is insufficient, which is common in many populations . This article synthesizes research findings on the efficacy, preferences, and health impacts of calcium supplement tablets.
Calcium supplements, whether in tablet form or as part of dietary interventions, have been shown to significantly increase calcium intake and improve overall nutrient profiles. In a study involving postmenopausal women, those who took calcium tablets had higher calcium intakes compared to those who used skim milk powder, and they also showed reduced dietary fat intake and plasma cholesterol levels. Additionally, calcium supplementation combined with vitamin D has been found to enhance the beneficial effects of weight loss on plasma lipid and lipoprotein concentrations, leading to improved cholesterol profiles in overweight or obese women.
The bioavailability of calcium from supplements can vary based on the form of calcium and the presence of other nutrients. Calcium carbonate, a common form of calcium supplement, has been shown to be as effective as milk in increasing calcium absorption, especially when combined with vitamin D. However, the absorption of calcium carbonate can be hindered in individuals with low stomach acid, making chelated calcium salts a better option for these individuals .
The form of calcium supplements significantly affects their acceptability and long-term adherence. In a study conducted in Dhaka, Bangladesh, conventional calcium tablets were preferred over chewable tablets and powdered forms due to their palatability and ease of use. Conventional tablets had a 62% probability of being selected daily, compared to much lower probabilities for other forms. This preference highlights the importance of considering user acceptability when designing calcium supplementation programs.
Gastrointestinal (GI) side effects are a common concern with calcium supplements. A study on postmenopausal women found that microencapsulated calcium carbonate (microCaCO3) had better GI tolerability compared to conventional calcium carbonate tablets. Participants reported fewer GI symptoms and higher satisfaction with microCaCO3, suggesting that this form may improve compliance with calcium supplementation.
Calcium supplementation has a positive impact on bone mineral density (BMD), particularly in populations at risk of osteoporosis. A study on adolescent female twins showed that calcium supplementation led to a significant increase in BMD at the spine and hip, with the greatest effect observed in the first six months of supplementation. This finding underscores the importance of adequate calcium intake during critical periods of bone development.
Calcium supplementation during pregnancy has been associated with reduced risks of preterm delivery and low birth weight. A clinical trial involving pregnant adolescents found that those who received calcium supplements had lower incidences of preterm delivery and low birth weight compared to those who received a placebo. This suggests that calcium supplementation can be a valuable intervention for improving pregnancy outcomes in high-risk populations.
Calcium supplement tablets are an effective means of increasing calcium intake and improving various health outcomes, including bone density and lipid profiles. Preferences for supplement form and GI tolerability are crucial for ensuring long-term adherence. Overall, calcium supplementation, particularly when combined with vitamin D, offers significant health benefits and should be considered in populations with low dietary calcium intake.
Most relevant research papers on this topic