Can vitamins make you nauseous
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Can Vitamins Make You Nauseous?
Introduction to Vitamin-Induced Nausea
Vitamins are essential nutrients that support various bodily functions, but their intake can sometimes lead to adverse effects, including nausea. This article explores the relationship between vitamin consumption and nausea, drawing on recent research findings.
Vitamin B6 and Nausea Relief
Vitamin B6 for Pregnancy-Related Nausea
Vitamin B6, also known as pyridoxine, has been studied extensively for its role in alleviating nausea, particularly in pregnant women. A randomized, double-blind placebo-controlled study involving 59 women demonstrated that vitamin B6 significantly reduced the severity of nausea and the number of vomiting episodes in those with severe nausea during pregnancy 1. This suggests that vitamin B6 can be an effective treatment for nausea and vomiting in pregnancy.
Comparison with Ginger
Another study compared the effectiveness of ginger and vitamin B6 in treating nausea and vomiting in early pregnancy. The results indicated that while both treatments were effective in reducing vomiting episodes, ginger was more effective than vitamin B6 in alleviating the severity of nausea 2. This highlights that while vitamin B6 is beneficial, other natural remedies like ginger might offer superior relief for some individuals.
Chemotherapy-Induced Nausea in Children
Vitamin B6 has also been tested for its efficacy in reducing chemotherapy-induced nausea and vomiting (CINV) in pediatric cancer patients. A clinical trial involving 100 children found that vitamin B6 significantly decreased both the severity of nausea and the frequency of vomiting compared to a placebo 3. This underscores the potential of vitamin B6 as a supportive treatment for managing CINV in children.
Conclusion
While vitamin B6 has been shown to effectively reduce nausea and vomiting in various contexts, including pregnancy and chemotherapy, it is important to note that individual responses can vary. Additionally, other treatments like ginger may sometimes offer better relief. Therefore, it is crucial to consult healthcare providers to determine the most appropriate treatment for nausea based on individual needs and circumstances.
Sources and full results
Most relevant research papers on this topic
Vitamin B6 is effective therapy for nausea and vomiting of pregnancy: A randomized, double‐blind placebo‐controlled study
Vitamin B6 therapy significantly reduced the severity of nausea and the number of patients with vomiting in pregnant women with severe nausea compared to placebo.
RCT
Highly CitedComparing ginger and vitamin B6 for the treatment of nausea and vomiting in pregnancy: a randomised controlled trial.
Ginger is more effective than vitamin B6 for relieving nausea severity and is equally effective for decreasing the number of vomiting episodes in early pregnancy.
RCTHighly CitedThe effect of Vitamin B6 on chemotherapy induced nausea and vomiting in pediatric cancer
Vitamin B6 significantly reduces chemotherapy-induced nausea and vomiting in children with malignancy, especially in acute lymphocytic leukemia.
RCT
Very Rigorous JournalDietary supplement-induced vitamin D intoxication.
Dietary supplements can cause vitamin D intoxication, causing fatigue, constipation, back pain, forgetfulness, nausea, and vomiting, and should be carefully evaluated for potential risks.
Case ReportInterventions with vitamins B6, B12 and C in pregnancy.
Vitamin C supplementation during pregnancy is not justified, while vitamin B6 supplementation may improve birthweight and reduce neural tube defects in offspring, but more research is needed.
Meta-AnalysisHighly CitedEfficacy of Vitamin C with Iron Supplementation in Iron Deficiency Anemia Patients: A Systematic Review and Meta-Analysis
Oral iron supplementation with vitamin C may slightly improve hemoglobin levels and ferritin levels in patients with iron deficiency anemia, but does not significantly differ in adverse effects.
Meta-AnalysisSupplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise.
Vitamin C and N-acetyl-cysteine supplementation after an acute muscle injury can transiently increase tissue damage and oxidative stress.
RCTHighly CitedAN OVERVIEW OF THE LEVEL OF KNOWLEDGE ON SELF-MEDICATING VITAMIN C STUDENTS D III PHARMACY STIKES WDH TANGERANG DURING THE COVID-19 PANDEMIC
During the Covid-19 pandemic, 96.88% of D III Pharmacy students at STIKes Widya Dharma Husada Tangerang had a "Good" knowledge of self-medicating with vitamin C.
Systematic review with meta‐analysis: The effect of vitamin E supplementation in adult patients with non‐alcoholic fatty liver disease
Vitamin E supplementation may improve biochemical and histological parameters in adult patients with non-alcoholic fatty liver disease.
Meta-Analysis
Rigorous JournalEffect of vitamin E supplementation on aminotransferase levels in patients with NAFLD, NASH, and CHC: results from a meta-analysis.
Vitamin E supplementation can optimize aminotransferase levels for patients with NAFLD, NASH, and CHC, but not significantly for NAFLD patients.
Meta-Analysis