Higher levels of cannabis use are associated with increased risk of psychosis, with a dose-response relationship between use and the risk for psychosis.

Meta-analysis of the Association Between the Level of Cannabis Use and Risk of Psychosis.

Cannabis use increases the risk of developing psychosis by twofold, and discouraging its use could potentially prevent psychotic disorders among vulnerable youths.

Causal association between cannabis and psychosis: examination of the evidence

Cannabis use increases the risk of psychotic outcomes, with greater risk in frequent users, and there is sufficient evidence to warn young people about the risk of developing a psychotic illness later in life.

Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review

Heavy use of high-THC/low-CBD types of cannabis increases the risk of psychosis, while evidence for mania and suicide is growing but less convincing for depression and anxiety.

Cannabis Use and the Risk for Psychosis and Affective Disorders

Cannabis use doubles the risk of developing psychosis in vulnerable individuals, with dose and age of first use playing a role, and gene-environment interactions modulating this association.

Cannabis consumption and psychosis or schizophrenia development

Cannabis use is associated with a higher risk of developing psychotic illness, earlier onset, increased relapse rates, more hospitalizations, and pronounced positive symptoms in psychotic patients.

Cannabis use and psychosis: a review of reviews

Frequent cannabis use increases the risk of psychosis, with no significant risk associated with less frequent use.

Risk-thresholds for the association between frequency of cannabis use and the development of psychosis: a systematic review and meta-analysis

Current cannabis abuse or dependence is significantly associated with transition to psychosis in individuals at ultra-high risk for psychosis, suggesting a dose-response relationship.

Cannabis use and transition to psychosis in individuals at ultra-high risk: review and meta-analysis

Cannabis use increases the risk of psychosis by 40% in young adults, with a dose-response effect, leading to a 50-2000% increase in the most frequent users.

Cannabis use and risk of psychosis in later life

Cannabis use increases the risk of developing psychotic symptoms, but the causal nature of this association remains unclear.

Cannabis and Psychosis: What is the Link?

Cannabis use is associated with schizophrenia, but the relationship may be partly causal and partly confounded by genetic/familial effects and/or reverse causation.

Use of Genetically Informed Methods to Clarify the Nature of the Association Between Cannabis Use and Risk for Schizophrenia.

Cannabis use can increase the risk of psychotic disorders, warranting a public health message.

Association Between Cannabis and Psychosis: Epidemiologic Evidence

Cannabis use is associated with an increased risk of nonaffective psychosis, but more research is needed to address gene-environment correlations and underlying biological mechanisms.

Epidemiological, neurobiological, and genetic clues to the mechanisms linking cannabis use to risk for nonaffective psychosis.

Exposure to cannabis increases the risk for psychosis, with greater risk at higher doses and earlier ages, and delaying or eliminating exposure could potentially impact rates of psychosis related to cannabis.

Consensus paper of the WFSBP task force on cannabis, cannabinoids and psychosis

Cannabis use is a risk factor for the development of psychosis in people at clinical high risk, but the direction of this association remains controversial.

Influence of cannabis use on incidence of psychosis in people at clinical high risk

Cannabis use, especially high-potency forms and synthetic cannabinoids, increases the risk of psychosis and negatively impacts cognitive function, especially when used early in life.

Traditional marijuana, high‐potency cannabis and synthetic cannabinoids: increasing risk for psychosis

Heavy cannabis use is strongly associated with increased risk of psychosis in individuals at ultrahigh risk for developing the disorder, highlighting the need for targeted prevention and research.

Clarifying the link between cannabis use and risk for psychosis

Frequent, daily use of cannabis, and high-potency cannabis use increase the risk of developing psychosis, with genetic factors like AKT1 playing a moderating role.

Factors Moderating the Association between Cannabis Use and Psychosis Risk: A Systematic Review

Cannabis use is associated with psychosis, with six potential risk factors identified, while cannabidiol (CBD) shows a significant inverse relationship, suggesting less psychotic symptoms and antipsychotic properties.

Cannabis and Psychosis: A Review of the Risk Factors Involved

Cannabis use is a modest risk factor for psychosis, with potential risks higher among frequent users, potent cannabis users, and those with specific genetic or neurobiological vulnerability.

Is there sufficient evidence that cannabis use is a risk factor for psychosis?

Is there any causal evidence on the link between cannabis consumption and psychosis risk?

These studies suggest that cannabis use is associated with an increased risk of developing psychosis, particularly with higher frequency and potency of use, though the causal nature of this relationship remains debated.