is dandellion root good for the liver?

Introduction

Dandelion root (Taraxacum officinale) has been traditionally used in herbal medicine for its potential health benefits, particularly for liver health. Recent scientific studies have investigated its effects on liver function, providing insights into its hepatoprotective properties.

Key Insights

Hepatoprotective Effects:
- Dandelion root extract (TOERE) has been shown to reduce serum liver injury markers and oxidative stress in a rat model of acute on chronic liver failure, indicating its potential for preventing liver damage.
- Dandelion root extract demonstrated therapeutic effects on carbon tetrachloride (CCl4)-induced liver fibrosis in mice by reducing hepatic fibrinous deposits and restoring histological architecture .
Antioxidant Properties:
- Dandelion root and leaf extracts have been found to positively affect plasma antioxidant enzyme activities and lipid profiles in cholesterol-fed rabbits, suggesting potential hypolipidemic and antioxidant effects.
- The antioxidant properties of dandelion root polysaccharides (DRP1 and DRP2) were shown to protect against acetaminophen-induced liver injury by activating the Nrf2-Keap1 pathway.
Anti-inflammatory and Antifibrotic Effects:
- Dandelion root extract has been reported to downregulate inflammatory markers and decrease collagen deposition in liver fibrosis models, highlighting its anti-inflammatory and antifibrotic properties.
- The extract also mitigated inflammatory signaling and oxidative stress in intestinal epithelial cells, further supporting its anti-inflammatory potential.
Liver Function Improvement:
- Supplementation with dandelion root in laying hens improved liver function by decreasing lipid profiles and liver fat ratio, indicating its role in preventing lipid peroxidation and enhancing liver health.

Conclusion

The collective findings from various studies suggest that dandelion root has significant hepatoprotective, antioxidant, anti-inflammatory, and antifibrotic properties. These effects make it a promising natural remedy for supporting liver health and preventing liver-related diseases.

Is dandellion root good for the liver?

Summary

Consensus Meter

Introduction

Key Insights

Conclusion

Sources and full results

Protective Effects of Taraxacum officinale L. (Dandelion) Root Extract in Experimental Acute on Chronic Liver Failure

Ethanolic Taraxacum officinale L. (dandelion) root extract shows hepatoprotective effects in acute on chronic liver failure, potentially due to oxidative stress reduction.

Beneficial uses of dandelion herb (Taraxacum officinale) in poultry nutrition

Dandelion herb can enhance poultry growth and productivity by improving digestion, liver function, and immune system health.

Antifibrotic activity of Taraxacum officinale root in carbon tetrachloride-induced liver damage in mice.

Dandelion root water-ethanol extract (DWE) effectively reduces carbon tetrachloride-induced liver fibrosis in mice by inactivating hepatic stellate cells and enhancing hepatic regenerative capabilities.

Dandelion root extract protects NCM460 colonic cells and relieves experimental mouse colitis

Dandelion root extract shows strong cytoprotective effects on colonic cells and effectively relieves experimental mouse colitis, offering a complementary alternative to current therapeutic interventions.

Hypolipidemic and Antioxidant Effects of Dandelion (Taraxacum officinale) Root and Leaf on Cholesterol-Fed Rabbits

Dandelion root and leaf show potential hypolipidemic and antioxidant effects in cholesterol-fed rabbits, potentially protecting against oxidative stress-linked atherosclerosis and decreasing the atherogenic index.

Protective role of the dandelion extract against the blood–liver axis, cell membranes, and anemia disorder in sodium benzoate‐exposed rats

Dandelion extract can prevent liver and kidney injury, and reduce anemia, neutropenia, thrombocytopenia, hyperproteinemia, hyperglycemia, and inflammation in sodium benzoate-exposed rats.

Effects of Dandelion (Taraxacum officinale) Supplementation on Productive Performance, Egg Quality Traits, Serum Biochemical Parameters and Liver Fat Rate in Laying Hens

Dandelion root supplementation at 5 g/kg in high-energy feed improves egg production, decreases lipid profiles, and prevents liver fat ratio in laying hens.

Purification, Preliminary Characterization and Hepatoprotective Effects of Polysaccharides from Dandelion Root

Dandelion root polysaccharides DRP1 and DRP2 show potential as functional foods and natural drugs to prevent acetaminophen-induced liver injury by activating the Nrf2-Keap1 pathway.

Dandelion prevents liver fibrosis, inflammatory response, and oxidative stress in rats

Dandelion root extract prevents liver fibrosis progression in rats by improving liver histology, decreasing collagen deposition, and reducing inflammation and oxidative stress.

Dandelion extract suppresses reactive oxidative species and inflammasome in intestinal epithelial cells

Dandelion extract suppresses inflammation by scavenging reactive oxygen species and inhibiting inflammasome activation, with chicoric acid being the main component responsible for these beneficial effects.

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