Diabetes tablets names
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Overview of Diabetes Tablets: Names and Efficacy
Introduction to Diabetes Tablets
Diabetes tablets, also known as oral hypoglycemic agents, are medications used to manage blood sugar levels in individuals with type 2 diabetes. These tablets do not contain insulin but work by either stimulating the pancreas to produce more insulin or by increasing the effectiveness of the insulin that the body already produces . This article provides an overview of various diabetes tablets, their names, and their clinical efficacy.
JinQi-Jiangtang Tablets for Pre-Diabetes
Efficacy and Safety
JinQi-Jiangtang (JQJT) tablets are a traditional Chinese medicine used for managing pre-diabetes. Clinical trials have shown that JQJT tablets can effectively reduce the incidence of diabetes and improve reversion rates from pre-diabetes to normal glucose levels . The tablets have been found to lower fasting blood glucose (FBG), 2-hour postprandial blood glucose (2hPG), and glycosylated hemoglobin (HbA1c) levels.
Cost-Effectiveness
A cost-effectiveness analysis revealed that JQJT tablets, combined with lifestyle education, offer a greater economic advantage in reducing the incidence of diabetes compared to lifestyle education alone.
Metformin Tablets: Standard and Sustained-Release
Clinical Efficacy
Metformin is one of the most commonly prescribed medications for type 2 diabetes. Studies comparing the standard metformin tablets (Glucophage) with metformin sustained-release (SR) tablets (Dulening) have shown that both forms are equally effective in reducing HbA1c and fasting blood glucose levels. However, the SR tablets have a lower incidence of gastrointestinal adverse drug reactions (ADRs).
Fixed-Dose Combination Tablets
Benefits and Examples
Fixed-dose combination tablets combine two or more oral hypoglycemic agents with different mechanisms of action into a single pill. These combinations improve patient adherence by reducing the pill burden and simplifying the medication regimen. Examples include:
- Metformin and Sulphonylurea
- Metformin and Thiazolidinedione
- Metformin and Dipeptidyl Peptidase-4 (DPP-4) Inhibitor
- Dapagliflozin and Saxagliptin (QTERN): This combination has shown efficacy as an add-on therapy to metformin, providing significant reductions in HbA1c levels.
Traditional Chinese Medicine: Tianmai Xiaoke Tablets
Efficacy in Newly Diagnosed T2DM
Tianmai Xiaoke tablets (TMXKT), which contain chromium, have been approved for treating newly diagnosed type 2 diabetes in China. Meta-analyses of randomized clinical trials indicate that TMXKT, when combined with conventional therapy, significantly lowers FBG, 2hPG, HbA1c, and body mass index (BMI) levels.
Conclusion
Diabetes tablets play a crucial role in managing type 2 diabetes by lowering blood sugar levels and improving overall glycemic control. From traditional Chinese medicines like JinQi-Jiangtang and Tianmai Xiaoke tablets to widely used medications like metformin and fixed-dose combinations, these tablets offer various options for effective diabetes management. Each type of tablet has its own set of benefits and potential side effects, making it essential for healthcare providers to tailor treatments to individual patient needs.
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