Searched over 200M research papers
10 papers analyzed
Some studies suggest artificial sweeteners may negatively impact gut microbiota and increase health risks, while other studies indicate more research is needed to confirm these effects in humans.
11 papers analyzed
20 papers analyzed
Artificial sweeteners (AS) are widely used as sugar substitutes in various food and beverage products. Despite their popularity, there is growing concern about their potential impact on gut health, particularly on the gut microbiome and gastrointestinal (GI) tract. This synthesis aims to analyze the current research on whether artificial sweeteners damage the gut.
Impact on Gut Microbiome Composition:
Pathogenicity and Biofilm Formation:
Antibiotic Resistance Gene Transfer:
Metabolic and Inflammatory Effects:
Glucose Intolerance and Metabolic Derangements:
Human vs. Animal Studies:
The current body of research suggests that artificial sweeteners can negatively impact gut health by altering the gut microbiome, increasing bacterial pathogenicity, promoting antibiotic resistance, and potentially exacerbating metabolic and inflammatory conditions. However, most of the evidence comes from animal studies, and more human research is needed to draw definitive conclusions.
Most relevant research papers on this topic