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Some studies suggest fish oil improves mood and mental health in certain populations, such as middle-aged adults and women with polycystic ovary syndrome, while other studies indicate it has little to no effect on mood in healthy young adults or as an add-on therapy for depression.
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Fish oil, rich in omega-3 polyunsaturated fatty acids (PUFAs), has been widely studied for its potential benefits on mood and mental health. This synthesis aims to evaluate whether fish oil supplementation can improve mood based on findings from multiple research studies.
General Mood Improvement in Specific Populations:
No Significant Effect in Healthy Young Adults and General Populations:
Potential Benefits in Depressed Individuals:
Mechanisms and Biological Markers:
Fish oil supplementation appears to have mixed effects on mood improvement. While it shows promise in specific populations such as non-depressed older adults, individuals with PCOS, and those following a Mediterranean-style diet, it does not consistently improve mood in healthy young adults or general populations. The potential benefits may be linked to its anti-inflammatory properties and effects on brain lipid composition and connectivity. Further research is needed to identify the populations that may benefit the most from fish oil supplementation for mood improvement.
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