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These studies suggest that a ketogenic diet may decrease depression by improving mood, stabilizing mood disorders, and affecting various biological systems, although clinical trials specifically for depression are lacking.
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The ketogenic diet (KD), characterized by high fat, moderate protein, and low carbohydrate intake, has been explored for its potential benefits beyond weight loss and epilepsy management. Recent research has investigated its effects on mood disorders, particularly depression. This synthesis aims to evaluate whether a ketogenic diet can decrease depression based on findings from multiple studies.
Antidepressant and Mood-Stabilizing Effects:
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Comparative Studies:
The ketogenic diet shows promise as a potential intervention for reducing depression, with evidence supporting its antidepressant and mood-stabilizing effects. The mechanisms likely involve improvements in neurotransmitter balance, mitochondrial function, and anti-inflammatory effects. While preclinical and observational studies are encouraging, more rigorous clinical trials are needed to confirm these findings and establish KD as a standard treatment for depression.
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